Skip to content


Sikeston is situated at the crossroads of Interstates 55 & 57, and at the junction of U.S. Highways 60, 61, 62 in Southeast Missouri.  We are located 140 miles equidistant between St. Louis and Memphis. Our central location, low electric rates and quality workforce make Sikeston an ideal place for manufacturing/distribution, and a great place to locate your business. Contact the Sikeston Economic Development Corp. and let us help you locate to our community.

Scroll To Top