• Certified Missouri

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      2018 Annual Banquet
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      Zaxby's Ribbon Cutting
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      Sikeston Rodeo Parade
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      Sikeston Rodeo Parade
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      Clinton Community Building
  • Welcome to Sikeston Regional Chamber & Area Economic Development Corporation

  • The Sikeston Regional Chamber is dedicated to promoting and improving the business community in our region. The Chamber works in partnership with businesses and local government to create an environment that is a great place to live, work, and shop. 

    We provide opportunities for businesses to increase their exposure and to build business relationships within our region through programs and events, inexpensive advertising, and networking opportunities.

    Our offices are located at 128 N. New Madrid St., Sikeston, Missouri. We invite you to stop to meet our friendly staff or call (573) 471-2498.

    We strive to create a friendly business and family environment that ensures the success of our community, businesses, and our members. Let us know how we can help you connect, grow, and succeed!

  • Innovative Economic Development
  • Click here for helpful information on opening a business in Sikeston.




  • Mark Your Calendar

  • New Members

    PURE Yoga


  • Corporate Sponsors